A 26-month-old boy presents to the outpatient clinic with a productive cough for the last five days. His mother reports a history of recurrent chest infections during the past year. He also has a history of chronic bloody diarrhea and pronounced bleeding after his circumcision. His blood pressure is 100/60 mm Hg, pulse is 100/min, temperature is 38.0°C (100.4°F), and respirations are 27/min. On examination, there are purpuric eruptions over the extremities and eczematous patches on the flexural surfaces of his elbows and knees. Chest auscultation reveals crepitus over the base of the right lung. Chest radiography is suggestive of consolidation in the right lower lobe. Blood test results show anemia, thrombocytopenia with small platelets, and leukopenia. With suspicion of congenital immunodeficiency, flow cytometry is ordered, which reveals a Wiskott-Aldrich syndrome protein (WASP) mutation. Which of the following would be the definitive treatment of this patient's condition?
A 31-year-old man and his wife were referred to a genetic counselor. They are concerned that their children could inherit certain conditions that run in their families. The wife's father and grandfather are both healthy, but her grandfather cannot see the color red. The husband is unaware if any family member has the same condition. The geneticist provides some details about genetic diseases and inheritance patterns, then orders laboratory tests to analyze the gene mutations in both partners. Which of the following are the correct descriptive terms regarding the genotype and phenotype of males affected by the condition described?
